Induced Tamoxifen Resistance is Mediated by Increased Methylation of E-Cadherin in Estrogen Receptor-Expressing Breast Cancer Cells

Estrogen receptor-positive breast cancers are treated with tamoxifen, a drug that competitively inhibits the binding of estrogen to its receptor. Resistance to tamoxifen is a major hurdle in effective management of target breast cancer patient population. A number of dynamic changes within the tumor...

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Detalles Bibliográficos
Autores principales: Wang, Qi, Gun, Melisa, Hong, Xing-yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775106/
https://www.ncbi.nlm.nih.gov/pubmed/31578396
http://dx.doi.org/10.1038/s41598-019-50749-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775106/
https://www.ncbi.nlm.nih.gov/pubmed/31578396
http://dx.doi.org/10.1038/s41598-019-50749-1

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