Fractional Deletion of Compound Kushen Injection Indicates Cytokine Signaling Pathways are Critical for its Perturbation of the Cell Cycle

We used computational and experimental biology approaches to identify candidate mechanisms of action of aTraditional Chinese Medicine, Compound Kushen Injection (CKI), in a breast cancer cell line (MDA-MB-231). Because CKI is a complex mixture of plant secondary metabolites, we used a high-performan...

Descripción completa

Detalles Bibliográficos
Autores principales: Aung, T. N., Nourmohammadi, S., Qu, Z., Harata-Lee, Y., Cui, J., Shen, H. Y., Yool, A. J., Pukala, T., Du, Hong, Kortschak, R. D., Wei, W., Adelson, D. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775143/
https://www.ncbi.nlm.nih.gov/pubmed/31578346
http://dx.doi.org/10.1038/s41598-019-50271-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775143/
https://www.ncbi.nlm.nih.gov/pubmed/31578346
http://dx.doi.org/10.1038/s41598-019-50271-4

Ejemplares similares