Cargando…

Nanopore device-based fingerprinting of RNA oligos and microRNAs enhanced with an Osmium tag

Protein and solid-state nanopores are used for DNA/RNA sequencing as well as for single molecule analysis. We proposed that selective labeling/tagging may improve base-to-base resolution of nucleic acids via nanopores. We have explored one specific tag, the Osmium tetroxide 2,2′-bipyridine (OsBp), w...

Descripción completa

Detalles Bibliográficos
Autores principales: Sultan, Madiha, Kanavarioti, Anastassia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775150/
https://www.ncbi.nlm.nih.gov/pubmed/31578367
http://dx.doi.org/10.1038/s41598-019-50459-8