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Nanopore device-based fingerprinting of RNA oligos and microRNAs enhanced with an Osmium tag
Protein and solid-state nanopores are used for DNA/RNA sequencing as well as for single molecule analysis. We proposed that selective labeling/tagging may improve base-to-base resolution of nucleic acids via nanopores. We have explored one specific tag, the Osmium tetroxide 2,2′-bipyridine (OsBp), w...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775150/ https://www.ncbi.nlm.nih.gov/pubmed/31578367 http://dx.doi.org/10.1038/s41598-019-50459-8 |