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Principles for enhancing virus capsid capacity and stability from a thermophilic virus capsid structure

The capsids of double-stranded DNA viruses protect the viral genome from the harsh extracellular environment, while maintaining stability against the high internal pressure of packaged DNA. To elucidate how capsids maintain stability in an extreme environment, we use cryoelectron microscopy to deter...

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Detalles Bibliográficos
Autores principales: Stone, Nicholas P., Demo, Gabriel, Agnello, Emily, Kelch, Brian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775164/
https://www.ncbi.nlm.nih.gov/pubmed/31578335
http://dx.doi.org/10.1038/s41467-019-12341-z