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Inhibiting Ceramide Synthesis Attenuates Hepatic Steatosis and Fibrosis in Rats With Non-alcoholic Fatty Liver Disease

Non-alcoholic fatty liver disease (NAFLD) is one of the most common metabolic disorder diseases, which include a histological spectrum of conditions ranging from simple steatosis to non-alcoholic steatohepatitis (NASH). Dysregulated metabolism of sphingomyelin in the liver plays a critical role in t...

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Detalles Bibliográficos
Autores principales: Jiang, Meng, Li, Chun, Liu, Qiaoshu, Wang, Aimin, Lei, Minxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775186/
https://www.ncbi.nlm.nih.gov/pubmed/31616384
http://dx.doi.org/10.3389/fendo.2019.00665