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Multiple myeloma increases nerve growth factor and other pain-related markers through interactions with the bone microenvironment
Interactions between multiple myeloma (MM) and bone marrow (BM) are well documented to support tumour growth, yet the cellular mechanisms underlying pain in MM are poorly understood. We have used in vivo murine models of MM to show significant induction of nerve growth factor (NGF) by the tumour-bea...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775275/ https://www.ncbi.nlm.nih.gov/pubmed/31578352 http://dx.doi.org/10.1038/s41598-019-50591-5 |