Pharmacological Blockade of Spinal CXCL3/CXCR2 Signaling by NVP CXCR2 20, a Selective CXCR2 Antagonist, Reduces Neuropathic Pain Following Peripheral Nerve Injury

Recently, the role of CXCR2 in nociception has been noted. Our studies provide new evidence that the intrathecal administration of its CINC ligands (Cytokine-Induced Neutrophil Chemoattractant; CXCL1-3) induces pain-like behavior in naïve mice, and the effect occurring shortly after administration i...

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Detalles Bibliográficos
Autores principales: Piotrowska, Anna, Rojewska, Ewelina, Pawlik, Katarzyna, Kreiner, Grzegorz, Ciechanowska, Agata, Makuch, Wioletta, Nalepa, Irena, Mika, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775284/
https://www.ncbi.nlm.nih.gov/pubmed/31616413
http://dx.doi.org/10.3389/fimmu.2019.02198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775284/
https://www.ncbi.nlm.nih.gov/pubmed/31616413
http://dx.doi.org/10.3389/fimmu.2019.02198

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