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Umbelliferone Prevents Lipopolysaccharide-Induced Bone Loss and Suppresses RANKL-Induced Osteoclastogenesis by Attenuating Akt-c-Fos-NFATc1 Signaling

Excessive bone resorption plays a central role in the development of inflammatory bone diseases, including osteoporosis and rheumatoid arthritis. Thus, identification of agents that can effectively suppress excessive osteoclast formation and function is crucial for the prevention and treatment of in...

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Detalles Bibliográficos
Autores principales: Kwak, Sung Chul, Baek, Jong Min, Lee, Chang Hoon, Yoon, Kwon-Ha, Lee, Myeung Su, Kim, Ju-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775311/
https://www.ncbi.nlm.nih.gov/pubmed/31595160
http://dx.doi.org/10.7150/ijbs.28609