Rictor ablation in BMSCs inhibits bone metastasis of TM40D cells by attenuating osteolytic destruction and CAF formation

The mTOR complex 2 (mTORC2) is recognized as a promising target for breast cancer treatment. As mTORC2-specific inhibitors do not yet exist, studies into the role of mTORC2 in cancer are performed by deleting Rictor or by RNAi-mediated Rictor silencing. The purpose of this study was to explore the e...

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Detalles Bibliográficos
Autores principales: Liu, Zibo, Wang, Hui, He, Jialing, Yuan, Xiaoqin, Sun, Weiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775318/
https://www.ncbi.nlm.nih.gov/pubmed/31595162
http://dx.doi.org/10.7150/ijbs.37241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775318/
https://www.ncbi.nlm.nih.gov/pubmed/31595162
http://dx.doi.org/10.7150/ijbs.37241

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