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Adjunctive granisetron therapy in patients with sepsis or septic shock (GRANTISS): Study protocol for a randomized controlled trial

INTRODUCTION: The incidence, mortality, and treatment costs of sepsis are high and, thus, present a major challenge for critical care medicine. Our previous studies suggest that intestinal metabolite granisetron has a potential therapeutic effect on sepsis. Granisetron is a clinically widely used an...

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Detalles Bibliográficos
Autores principales: Guan, Jianbin, Guo, Yuexun, Chang, Ping, Gan, Jianwei, Zhou, Jian, Wang, Hua, Cen, Zhongran, Tang, Ying, Liu, Zhanguo, Chen, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775362/
https://www.ncbi.nlm.nih.gov/pubmed/31574878
http://dx.doi.org/10.1097/MD.0000000000017354