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Group A Streptococcus Induces LAPosomes via SLO/β1 Integrin/NOX2/ROS Pathway in Endothelial Cells That Are Ineffective in Bacterial Killing and Suppress Xenophagy

Group A streptococcus (GAS) is an important human pathogen which can cause fatal diseases after invasion into the bloodstream. Although antibiotics and immune surveillance are the main defenses against GAS infection, GAS utilizes internalization into cells as a major immune evasion strategy. Our pre...

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Detalles Bibliográficos
Autores principales: Cheng, Yi-Lin, Kuo, Chih-Feng, Lu, Shiou-Ling, Hiroko, Omori, Wu, Ya-Na, Hsieh, Cheng-Lu, Noda, Takeshi, Wu, Shang-Rung, Anderson, Robert, Lin, Chiou-Feng, Chen, Chia-Ling, Wu, Jiunn-Jong, Lin, Yee-Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775456/
https://www.ncbi.nlm.nih.gov/pubmed/31575768
http://dx.doi.org/10.1128/mBio.02148-19