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Increased Epithelial Oxygenation Links Colitis to an Expansion of Tumorigenic Bacteria

Intestinal inflammation is a risk factor for colorectal cancer formation, but the underlying mechanisms remain unknown. Here, we investigated whether colitis alters the colonic microbiota to enhance its cancer-inducing activity. Colitis increased epithelial oxygenation in the colon of mice and drove...

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Detalles Bibliográficos
Autores principales: Cevallos, Stephanie A., Lee, Jee-Yon, Tiffany, Connor R., Byndloss, Austin J., Johnston, Luana, Byndloss, Mariana X., Bäumler, Andreas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775460/
https://www.ncbi.nlm.nih.gov/pubmed/31575772
http://dx.doi.org/10.1128/mBio.02244-19