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Establishment of Chronic Typhoid Infection in a Mouse Carriage Model Involves a Type 2 Immune Shift and T and B Cell Recruitment to the Gallbladder

Typhoid fever, caused primarily by Salmonella enterica serovar Typhi (S. Typhi), is a life-threatening systemic disease responsible for significant morbidity and mortality worldwide. Three to 5% of individuals infected with S. Typhi become chronic carriers due to bacterial persistence in the gallbla...

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Detalles Bibliográficos
Autores principales: González, Juan F., Kurtz, Jonathan, Bauer, David L., Hitt, Regan, Fitch, James, Wetzel, Amy, La Perle, Krista, White, Peter, McLachlan, James, Gunn, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775463/
https://www.ncbi.nlm.nih.gov/pubmed/31575775
http://dx.doi.org/10.1128/mBio.02262-19