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Activation of the leptin pathway by high expression of the long form of the leptin receptor (Ob-Rb) accelerates chondrocyte senescence in osteoarthritis

OBJECTIVES: Activation of the leptin pathway is closely correlated with human knee cartilage degeneration. However, the role of the long form of the leptin receptor (Ob-Rb) in cartilage degeneration needs further study. The aim of this study was to determine the effect of increasing the expression o...

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Detalles Bibliográficos
Autores principales: Zhao, Xiang, Huang, Ping, Li, Gen, Lv, Zhendong, Hu, Guangyu, Xu, Qingrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775539/
https://www.ncbi.nlm.nih.gov/pubmed/31588359
http://dx.doi.org/10.1302/2046-3758.89.BJR-2018-0325.R2