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Epigenetic activation of hepatocyte growth factor is associated with epithelial-mesenchymal transition and clinical outcome in non-small cell lung cancer

Hepatocyte growth factor (HGF) expression is repressed in normal differentiated lung epithelial cells, but its expression is aberrantly upregulated in non-small cell lung cancer (NSCLC) and acts as a poor prognostic factor. The underlying molecular mechanisms of aberrant HGF expression are unclear....

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Detalles Bibliográficos
Autores principales: Yin, Jun, Hu, Weimin, Xue, Xingyang, Fu, Wenfan, Dai, Lu, Jiang, Zeyong, Zhong, Shengpeng, Deng, Boyun, Zhao, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775597/
https://www.ncbi.nlm.nih.gov/pubmed/31602259
http://dx.doi.org/10.7150/jca.30034