Increase of secondary mutations may be a drug-resistance mechanism for lung adenocarcinoma after radiation therapy combined with tyrosine kinase inhibitor

Objective: To investigate changes in the secondary mutations of tumor in a drug-resistance mechanism for lung adenocarcinoma after radiation therapy combined with tyrosine kinase inhibitor (TKI). Methods: Lung adenocarcinoma cell line PC9 in vitro and xenograft model in nude mice were used to observ...

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Detalles Bibliográficos
Autores principales: Zhuang, Hongqing, Shi, Siyu, Guo, Yihang, Wang, Zhongqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775686/
https://www.ncbi.nlm.nih.gov/pubmed/31632481
http://dx.doi.org/10.7150/jca.35247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775686/
https://www.ncbi.nlm.nih.gov/pubmed/31632481
http://dx.doi.org/10.7150/jca.35247

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