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Tumor clonal status predicts clinical outcomes of lung adenocarcinoma with EGFR-TKI sensitizing mutation

Objectives: Intratumoral heterogeneity is one of major causes of resistance to therapeutic. Here, we evaluated clonal status, which may reflect intratumoral heterogeneity, in lung adenocarcinoma with EGFR-TKI sensitizing mutation (mEGFR) and its clinical implications. Materials and Methods: Customiz...

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Detalles Bibliográficos
Autores principales: Kim, Eun Young, Lee, Sang Hoon, Kim, Arum, Kim, Taehee, Chang, Yoon Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775702/
https://www.ncbi.nlm.nih.gov/pubmed/31632498
http://dx.doi.org/10.7150/jca.32897