Jejunal wall delivery of insulin via an ingestible capsule in anesthetized swine—A pharmacokinetic and pharmacodynamic study

Biotherapeutic agents must be administered parenterally to obtain therapeutic blood concentrations, lowering patient compliance and complicating care. An oral delivery platform (ODP) was developed to deliver drugs into the small intestinal wall. This proof‐of‐concept study was performed in 17 anesth...

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Detalles Bibliográficos
Autores principales: Hashim, Mir, Korupolu, Radhika, Syed, Baber, Horlen, Kyle, Beraki, Simret, Karamchedu, Padma, Dhalla, Arvinder K., Ruffy, Rodolphe, Imran, Mir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775958/
https://www.ncbi.nlm.nih.gov/pubmed/31584244
http://dx.doi.org/10.1002/prp2.522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775958/
https://www.ncbi.nlm.nih.gov/pubmed/31584244
http://dx.doi.org/10.1002/prp2.522

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