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Jejunal wall delivery of insulin via an ingestible capsule in anesthetized swine—A pharmacokinetic and pharmacodynamic study
Biotherapeutic agents must be administered parenterally to obtain therapeutic blood concentrations, lowering patient compliance and complicating care. An oral delivery platform (ODP) was developed to deliver drugs into the small intestinal wall. This proof‐of‐concept study was performed in 17 anesth...
Autores principales: | Hashim, Mir, Korupolu, Radhika, Syed, Baber, Horlen, Kyle, Beraki, Simret, Karamchedu, Padma, Dhalla, Arvinder K., Ruffy, Rodolphe, Imran, Mir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775958/ https://www.ncbi.nlm.nih.gov/pubmed/31584244 http://dx.doi.org/10.1002/prp2.522 |
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