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Small Molecule-Based Strategy Promotes Nucleus Pulposus Specific Differentiation of Adipose-Derived Mesenchymal Stem Cells

Adipose tissue-derived mesenchymal stem cells (ADSCs) are promising for regenerating degenerated intervertebral discs (IVDs), but the low efficiency of nucleus pulposus (NP)-specific differentiation limits their clinical applications. The Sonic hedgehog (Shh) signaling pathway is important in NP-spe...

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Detalles Bibliográficos
Autores principales: Hua, Jianming, Shen, Ning, Wang, Jingkai, Tao, Yiqing, Li, Fangcai, Chen, Qixin, Zhou, Xiaopeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776160/
https://www.ncbi.nlm.nih.gov/pubmed/31564076
http://dx.doi.org/10.14348/molcells.2019.0098