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Small Molecule-Based Strategy Promotes Nucleus Pulposus Specific Differentiation of Adipose-Derived Mesenchymal Stem Cells
Adipose tissue-derived mesenchymal stem cells (ADSCs) are promising for regenerating degenerated intervertebral discs (IVDs), but the low efficiency of nucleus pulposus (NP)-specific differentiation limits their clinical applications. The Sonic hedgehog (Shh) signaling pathway is important in NP-spe...
Autores principales: | Hua, Jianming, Shen, Ning, Wang, Jingkai, Tao, Yiqing, Li, Fangcai, Chen, Qixin, Zhou, Xiaopeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Molecular and Cellular Biology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776160/ https://www.ncbi.nlm.nih.gov/pubmed/31564076 http://dx.doi.org/10.14348/molcells.2019.0098 |
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