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Genome profiling revealed the activation of IL2RG/JAK3/STAT5 in peripheral T-cell lymphoma expressing the ITK-SYK fusion gene
Peripheral T-cell lymphomas (PTCLs) are heterogeneous malignancies that are types of non-Hodgkin lymphomas; patients with this disease have poor prognoses. The IL-2-inducible T-cell kinase-spleen tyrosine kinase (ITK-SYK) fusion gene, the first recurrent chromosome translocation in PTCL-not otherwis...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776186/ https://www.ncbi.nlm.nih.gov/pubmed/31545408 http://dx.doi.org/10.3892/ijo.2019.4882 |