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Genome profiling revealed the activation of IL2RG/JAK3/STAT5 in peripheral T-cell lymphoma expressing the ITK-SYK fusion gene

Peripheral T-cell lymphomas (PTCLs) are heterogeneous malignancies that are types of non-Hodgkin lymphomas; patients with this disease have poor prognoses. The IL-2-inducible T-cell kinase-spleen tyrosine kinase (ITK-SYK) fusion gene, the first recurrent chromosome translocation in PTCL-not otherwis...

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Detalles Bibliográficos
Autores principales: Zhang, Lei-Lei, Pan, Hua-Xiong, Wang, Yi-Xuan, Guo, Tao, Liu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776186/
https://www.ncbi.nlm.nih.gov/pubmed/31545408
http://dx.doi.org/10.3892/ijo.2019.4882