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Penetration of linezolid into bone tissue 24 h after administration in patients with multidrug-resistant spinal tuberculosis

BACKGROUND: Linezolid has shown strong antimicrobial activity against multidrug-resistant (MDR)/rifampin-resistant strains of Mycobacterium tuberculosis. Linezolid achieves clinical efficacy mainly through area under the concentration time curve/minimum inhibitory concentration ratio in the infected...

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Detalles Bibliográficos
Autores principales: Li, Yuan, Huang, Hairong, Dong, Weijie, Lan, Tinglong, Fan, Jun, Wen, Shu’an, Zhang, Tingting, Qin, Shibing, Guo, Ai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776296/
https://www.ncbi.nlm.nih.gov/pubmed/31581274
http://dx.doi.org/10.1371/journal.pone.0223391