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Penetration of linezolid into bone tissue 24 h after administration in patients with multidrug-resistant spinal tuberculosis
BACKGROUND: Linezolid has shown strong antimicrobial activity against multidrug-resistant (MDR)/rifampin-resistant strains of Mycobacterium tuberculosis. Linezolid achieves clinical efficacy mainly through area under the concentration time curve/minimum inhibitory concentration ratio in the infected...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776296/ https://www.ncbi.nlm.nih.gov/pubmed/31581274 http://dx.doi.org/10.1371/journal.pone.0223391 |