Analytical validation of the Target Selector ctDNA platform featuring single copy detection sensitivity for clinically actionable EGFR, BRAF, and KRAS mutations

BACKGROUND: Personalized medicine requires accurate molecular profiling for targeted therapy decisions. Insufficient tissue yield or tumor heterogeneity frequently limits the correct tissue biomarker determination. As a noninvasive complement to traditional tissue biopsies, liquid biopsies detect an...

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Detalles Bibliográficos
Autores principales: Poole, Jason C., Wu, Shan-Fu, Lu, Timothy T., Vibat, Cecile Rose T., Pham, Anh, Samuelsz, Errin, Patel, Manisha, Chen, Jeffrey, Daher, Tony, Singh, Veena M., Arnold, Lyle J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776432/
https://www.ncbi.nlm.nih.gov/pubmed/31581267
http://dx.doi.org/10.1371/journal.pone.0223112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776432/
https://www.ncbi.nlm.nih.gov/pubmed/31581267
http://dx.doi.org/10.1371/journal.pone.0223112

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