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A single H/ACA small nucleolar RNA mediates tumor suppression downstream of oncogenic RAS

Small nucleolar RNAs (snoRNAs) are a diverse group of non-coding RNAs that direct chemical modifications at specific residues on other RNA molecules, primarily on ribosomal RNA (rRNA). SnoRNAs are altered in several cancers; however, their role in cell homeostasis as well as in cellular transformati...

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Detalles Bibliográficos
Autores principales: McMahon, Mary, Contreras, Adrian, Holm, Mikael, Uechi, Tamayo, Forester, Craig M, Pang, Xiaming, Jackson, Cody, Calvert, Meredith E, Chen, Bin, Quigley, David A, Luk, John M, Kelley, R Kate, Gordan, John D, Gill, Ryan M, Blanchard, Scott C, Ruggero, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776443/
https://www.ncbi.nlm.nih.gov/pubmed/31478838
http://dx.doi.org/10.7554/eLife.48847