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The Effect of 2-Ketobutyrate on Mitochondrial Substrate-Level Phosphorylation

The reaction catalyzed by succinate-CoA ligase in the mitochondrial matrix yields a high-energy phosphate when operating towards hydrolysis of the thioester bond of succinyl-CoA, known as mitochondrial substrate-level phosphorylation (mSLP). The catabolism of several metabolites converge to succinyl...

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Detalles Bibliográficos
Autores principales: Bui, David, Ravasz, Dora, Chinopoulos, Christos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776489/
https://www.ncbi.nlm.nih.gov/pubmed/30810978
http://dx.doi.org/10.1007/s11064-019-02759-8