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Centrosomal and ciliary targeting of CCDC66 requires cooperative action of centriolar satellites, microtubules and molecular motors

Mammalian centrosomes and cilia play key roles in many cellular processes and their deregulation is linked to cancer and ciliopathies. Spatiotemporal regulation of their biogenesis and function in response to physiological stimuli requires timely protein targeting. This can occur by different pathwa...

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Detalles Bibliográficos
Autores principales: Conkar, Deniz, Bayraktar, Halil, Firat-Karalar, Elif Nur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776500/
https://www.ncbi.nlm.nih.gov/pubmed/31582766
http://dx.doi.org/10.1038/s41598-019-50530-4