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Centrosomal and ciliary targeting of CCDC66 requires cooperative action of centriolar satellites, microtubules and molecular motors
Mammalian centrosomes and cilia play key roles in many cellular processes and their deregulation is linked to cancer and ciliopathies. Spatiotemporal regulation of their biogenesis and function in response to physiological stimuli requires timely protein targeting. This can occur by different pathwa...
Autores principales: | Conkar, Deniz, Bayraktar, Halil, Firat-Karalar, Elif Nur |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776500/ https://www.ncbi.nlm.nih.gov/pubmed/31582766 http://dx.doi.org/10.1038/s41598-019-50530-4 |
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