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Genetic risk for Alzheimer’s dementia predicts motor deficits through multi-omic systems in older adults

Alzheimer’s disease manifests with both cognitive and motor deficits. However, the degree to which genetic risk of Alzheimer’s dementia contributes to late-life motor impairment, and the specific molecular systems underlying these associations, are uncertain. Here, we adopted an integrative multi-om...

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Detalles Bibliográficos
Autores principales: Tasaki, Shinya, Gaiteri, Chris, Petyuk, Vladislav A., Blizinsky, Katherine D., De Jager, Philip L., Buchman, Aron S., Bennett, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776503/
https://www.ncbi.nlm.nih.gov/pubmed/31582723
http://dx.doi.org/10.1038/s41398-019-0577-4