A mechanism for the activation of the mechanosensitive Piezo1 channel by the small molecule Yoda1

Mechanosensitive Piezo1 and Piezo2 channels transduce various forms of mechanical forces into cellular signals that play vital roles in many important biological processes in vertebrate organisms. Besides mechanical forces, Piezo1 is selectively activated by micromolar concentrations of the small mo...

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Detalles Bibliográficos
Autores principales: Botello-Smith, Wesley M., Jiang, Wenjuan, Zhang, Han, Ozkan, Alper D., Lin, Yi-Chun, Pham, Christine N., Lacroix, Jérôme J., Luo, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776524/
https://www.ncbi.nlm.nih.gov/pubmed/31582801
http://dx.doi.org/10.1038/s41467-019-12501-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776524/
https://www.ncbi.nlm.nih.gov/pubmed/31582801
http://dx.doi.org/10.1038/s41467-019-12501-1

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