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A mechanism for the activation of the mechanosensitive Piezo1 channel by the small molecule Yoda1
Mechanosensitive Piezo1 and Piezo2 channels transduce various forms of mechanical forces into cellular signals that play vital roles in many important biological processes in vertebrate organisms. Besides mechanical forces, Piezo1 is selectively activated by micromolar concentrations of the small mo...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776524/ https://www.ncbi.nlm.nih.gov/pubmed/31582801 http://dx.doi.org/10.1038/s41467-019-12501-1 |