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Inhibition of Rac1-dependent forgetting alleviates memory deficits in animal models of Alzheimer’s disease
Accelerated forgetting has been identified as a feature of Alzheimer’s disease (AD), but the therapeutic efficacy of the manipulation of biological mechanisms of forgetting has not been assessed in AD animal models. Ras-related C3 botulinum toxin substrate 1 (Rac1), a small GTPase, has been shown to...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Higher Education Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776562/ https://www.ncbi.nlm.nih.gov/pubmed/31321704 http://dx.doi.org/10.1007/s13238-019-0641-0 |