Inhibition of Rac1-dependent forgetting alleviates memory deficits in animal models of Alzheimer’s disease

Accelerated forgetting has been identified as a feature of Alzheimer’s disease (AD), but the therapeutic efficacy of the manipulation of biological mechanisms of forgetting has not been assessed in AD animal models. Ras-related C3 botulinum toxin substrate 1 (Rac1), a small GTPase, has been shown to...

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Detalles Bibliográficos
Autores principales: Wu, Wenjuan, Du, Shuwen, Shi, Wei, Liu, Yunlong, Hu, Ying, Xie, Zuolei, Yao, Xinsheng, Liu, Zhenyu, Ma, Weiwei, Xu, Lin, Ma, Chao, Zhong, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776562/
https://www.ncbi.nlm.nih.gov/pubmed/31321704
http://dx.doi.org/10.1007/s13238-019-0641-0

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