Upregulation of GLT-1 via PI3K/Akt Pathway Contributes to Neuroprotection Induced by Dexmedetomidine

Perioperative ischemic stroke usually leads to neurological dysfunction caused by neuron death. During the ischemic condition, excitotoxity due to extracellular glutamate accumulation is a main mechanism of neuron damage. The clearance of glutamate mainly depends on glutamate transporter-1 (GLT-1) w...

Descripción completa

Detalles Bibliográficos
Autores principales: Peng, Mengyuan, Ling, Xiaomin, Song, Ruixue, Gao, Xuan, Liang, Zhifeng, Fang, Fang, Cang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776610/
https://www.ncbi.nlm.nih.gov/pubmed/31611842
http://dx.doi.org/10.3389/fneur.2019.01041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776610/
https://www.ncbi.nlm.nih.gov/pubmed/31611842
http://dx.doi.org/10.3389/fneur.2019.01041

Ejemplares similares