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Insulin-producing organoids engineered from islet and amniotic epithelial cells to treat diabetes
Maintaining long-term euglycemia after intraportal islet transplantation is hampered by the considerable islet loss in the peri-transplant period attributed to inflammation, ischemia and poor angiogenesis. Here, we show that viable and functional islet organoids can be successfully generated from di...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776618/ https://www.ncbi.nlm.nih.gov/pubmed/31582751 http://dx.doi.org/10.1038/s41467-019-12472-3 |