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Type I toxin-dependent generation of superoxide affects the persister life cycle of Escherichia coli

Induction of growth stasis by bacterial toxins from chromosomal toxin-antitoxin systems is suspected to favor formation of multidrug-tolerant cells, named persisters. Recurrent infections are often attributed to resuscitation and regrowth of persisters upon termination of antibiotic therapy. Several...

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Detalles Bibliográficos
Autores principales: Edelmann, Daniel, Berghoff, Bork A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776643/
https://www.ncbi.nlm.nih.gov/pubmed/31582786
http://dx.doi.org/10.1038/s41598-019-50668-1