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Type I toxin-dependent generation of superoxide affects the persister life cycle of Escherichia coli
Induction of growth stasis by bacterial toxins from chromosomal toxin-antitoxin systems is suspected to favor formation of multidrug-tolerant cells, named persisters. Recurrent infections are often attributed to resuscitation and regrowth of persisters upon termination of antibiotic therapy. Several...
Autores principales: | Edelmann, Daniel, Berghoff, Bork A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776643/ https://www.ncbi.nlm.nih.gov/pubmed/31582786 http://dx.doi.org/10.1038/s41598-019-50668-1 |
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