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IL-6-driven FasL promotes NF-κBp65/PUMA-mediated apoptosis in portal hypertensive gastropathy

Mucosal epithelial apoptosis with non-specific inflammation is an essential pathological characteristic in portal hypertensive gastropathy (PHG). However, whether a coordinated crosstalk between myeloid cells and epithelial cells involved in PHG remains unclear. IL-6, which is induced in the mucosa...

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Detalles Bibliográficos
Autores principales: Tan, Siwei, Xu, Minyi, Ke, Bilun, Lu, Yu, Liu, Huiling, Jiang, Jie, Wu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776649/
https://www.ncbi.nlm.nih.gov/pubmed/31582729
http://dx.doi.org/10.1038/s41419-019-1954-x