Stimulator of interferon genes (STING) activation exacerbates experimental colitis in mice

Detection of cytoplasmic DNA by the host’s innate immune system is essential for microbial and endogenous pathogen recognition. In mammalian cells, an important sensor is the stimulator of interferon genes (STING) protein, which upon activation by bacterially-derived cyclic dinucleotides (cDNs) or c...

Descripción completa

Detalles Bibliográficos
Autores principales: Martin, Gary R., Blomquist, Charlene M., Henare, Kimiora L., Jirik, Frank R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776661/
https://www.ncbi.nlm.nih.gov/pubmed/31582793
http://dx.doi.org/10.1038/s41598-019-50656-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776661/
https://www.ncbi.nlm.nih.gov/pubmed/31582793
http://dx.doi.org/10.1038/s41598-019-50656-5

Ejemplares similares