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Green Synthesis of Substituted Anilines and Quinazolines from Isatoic Anhydride-8-amide

Synthetic methods used to generate substituted anilines and quinazolines, both privileged pharmacological structures, are cumbersome, hazardous or, in some cases, unavailable. We developed a straightforward method for making isatoic anhydride-8-amide from isatin-7-carboxylic acid as a tool to easily...

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Detalles Bibliográficos
Autores principales: Gondi, Sudershan R., Bera, Asim K., Westover, Kenneth D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776664/
https://www.ncbi.nlm.nih.gov/pubmed/31582788
http://dx.doi.org/10.1038/s41598-019-50776-y