Secukinumab attenuates reactive astrogliosis via IL‐17RA/(C/EBPβ)/SIRT1 pathway in a rat model of germinal matrix hemorrhage

AIMS: Reactive astrogliosis plays a critical role in neurological deficits after germinal matrix hemorrhage (GMH). It has been reported that interleukin‐17A and IL‐17A receptor IL‐17RA/(C/EBPβ)/SIRT1 signaling pathway enhances reactive astrogliosis after brain injuries. We evaluated the effects of s...

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Detalles Bibliográficos
Autores principales: Liu, Sheng‐Peng, Huang, Lei, Flores, Jerry, Ding, Yan, Li, Peng, Peng, Jun, Zuo, Gang, Zhang, John H., Lu, Jun, Tang, Ji‐Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776744/
https://www.ncbi.nlm.nih.gov/pubmed/31020769
http://dx.doi.org/10.1111/cns.13144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776744/
https://www.ncbi.nlm.nih.gov/pubmed/31020769
http://dx.doi.org/10.1111/cns.13144

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