Cargando…
Secukinumab attenuates reactive astrogliosis via IL‐17RA/(C/EBPβ)/SIRT1 pathway in a rat model of germinal matrix hemorrhage
AIMS: Reactive astrogliosis plays a critical role in neurological deficits after germinal matrix hemorrhage (GMH). It has been reported that interleukin‐17A and IL‐17A receptor IL‐17RA/(C/EBPβ)/SIRT1 signaling pathway enhances reactive astrogliosis after brain injuries. We evaluated the effects of s...
Autores principales: | Liu, Sheng‐Peng, Huang, Lei, Flores, Jerry, Ding, Yan, Li, Peng, Peng, Jun, Zuo, Gang, Zhang, John H., Lu, Jun, Tang, Ji‐Ping |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776744/ https://www.ncbi.nlm.nih.gov/pubmed/31020769 http://dx.doi.org/10.1111/cns.13144 |
Ejemplares similares
-
Secukinumab: The Anti-IL-17A Biologic for the Treatment of Psoriasis
por: Fargnoli, Maria Concetta
Publicado: (2019) -
Genetic association of IL2RA, IL17RA, IL23R, and IL31RA single nucleotide polymorphisms with alopecia areata
por: Alghamdi, Mansour A., et al.
Publicado: (2022) -
Role of N-formyl peptide receptor 2 in germinal matrix hemorrhage: an intrinsic review of a hematoma resolving pathway
por: Flores, Jerry, et al.
Publicado: (2023) -
Germinal matrix hemorrhage-intraventricular hemorrhage: pathogenesis and outcomes
por: Piro, Ettore
Publicado: (2015) -
IL-17-induced dimerization of IL-17RA drives the formation of the IL-17 signalosome to potentiate signaling
por: Goepfert, Arnaud, et al.
Publicado: (2022)