The role of Xist‐mediated Polycomb recruitment in the initiation of X‐chromosome inactivation

Xist RNA has been established as the master regulator of X‐chromosome inactivation (XCI) in female eutherian mammals, but its mechanism of action remains unclear. By creating novel Xist‐inducible mutants at the endogenous locus in male mouse embryonic stem (ES) cells, we dissect the role of the cons...

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Detalles Bibliográficos
Autores principales: Bousard, Aurélie, Raposo, Ana Cláudia, Żylicz, Jan Jakub, Picard, Christel, Pires, Vanessa Borges, Qi, Yanyan, Gil, Cláudia, Syx, Laurène, Chang, Howard Y, Heard, Edith, da Rocha, Simão Teixeira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776897/
https://www.ncbi.nlm.nih.gov/pubmed/31456285
http://dx.doi.org/10.15252/embr.201948019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776897/
https://www.ncbi.nlm.nih.gov/pubmed/31456285
http://dx.doi.org/10.15252/embr.201948019

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