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Partially inserted nascent chain unzips the lateral gate of the Sec translocon

The Sec translocon provides the lipid bilayer entry for ribosome‐bound nascent chains and thus facilitates membrane protein biogenesis. Despite the appreciated role of the native environment in the translocon:ribosome assembly, structural information on the complex in the lipid membrane is scarce. H...

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Detalles Bibliográficos
Autores principales: Kater, Lukas, Frieg, Benedikt, Berninghausen, Otto, Gohlke, Holger, Beckmann, Roland, Kedrov, Alexej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776908/
https://www.ncbi.nlm.nih.gov/pubmed/31379073
http://dx.doi.org/10.15252/embr.201948191