2-Deoxyglucose and Newcastle Disease Virus Synergize to Kill Breast Cancer Cells by Inhibition of Glycolysis Pathway Through Glyceraldehyde3-Phosphate Downregulation

Targeting cancer cells metabolism is promising strategy in inhibiting cancer cells progression that are known to exhibit increased aerobic glycolysis. We used the glucose analog 2-Deoxyglucose (2-DG) as a competitor molecule of glucose. To further enhance the effectiveness of 2-DG, the Newcastle dis...

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Detalles Bibliográficos
Autores principales: Al-Shammari, Ahmed Majeed, Abdullah, Amer Hasan, Allami, Zainab Majid, Yaseen, Nahi Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777003/
https://www.ncbi.nlm.nih.gov/pubmed/31612140
http://dx.doi.org/10.3389/fmolb.2019.00090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777003/
https://www.ncbi.nlm.nih.gov/pubmed/31612140
http://dx.doi.org/10.3389/fmolb.2019.00090

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