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Structure of an RNA helix with pyrimidine mismatches and cross-strand stacking

The structure of a 22-base-pair RNA helix with mismatched pyrimidine base pairs is reported. The helix contains two symmetry-related CUG sequences: a triplet-repeat motif implicated in myotonic dystrophy type 1. The CUG repeat contains a U–U mismatch sandwiched between Watson–Crick pairs. Additional...

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Detalles Bibliográficos
Autores principales:	Montemayor, Eric J., Virta, Johanna M., Hagler, Lauren D., Zimmerman, Steven C., Butcher, Samuel E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2019
Materias:	Research Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777134/ https://www.ncbi.nlm.nih.gov/pubmed/31584014 http://dx.doi.org/10.1107/S2053230X19012172

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