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High mobility group box protein 1 neutralization therapy in ovine bacteremia: Lessons learned from an ovine septic shock model incorporating intensive care support

Sepsis is a highly complex and often fatal syndrome which varies widely in its clinical manifestations, and therapies that target the underlying uncontrolled immune status in sepsis are needed. The failure of preclinical approaches to provide significant sepsis survival benefit in the clinic is ofte...

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Detalles Bibliográficos
Autores principales: Stevens, Natalie E., Nash, Coralie H., Fraser, Cara K., Kuchel, Tim R., Maiden, Matthew J., Chapman, Marianne J., Diener, Kerrilyn R., Hayball, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777221/
https://www.ncbi.nlm.nih.gov/pubmed/31602200
http://dx.doi.org/10.3892/etm.2019.7961