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Feedback loops in the Plk4–STIL–HsSAS6 network coordinate site selection for procentriole formation
Centrioles are duplicated once in every cell cycle, ensuring the bipolarity of the mitotic spindle. How the core components cooperate to achieve high fidelity in centriole duplication remains poorly understood. By live-cell imaging of endogenously tagged proteins in human cells throughout the entire...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777370/ https://www.ncbi.nlm.nih.gov/pubmed/31533936 http://dx.doi.org/10.1242/bio.047175 |