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Feedback loops in the Plk4–STIL–HsSAS6 network coordinate site selection for procentriole formation

Centrioles are duplicated once in every cell cycle, ensuring the bipolarity of the mitotic spindle. How the core components cooperate to achieve high fidelity in centriole duplication remains poorly understood. By live-cell imaging of endogenously tagged proteins in human cells throughout the entire...

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Detalles Bibliográficos
Autores principales: Takao, Daisuke, Watanabe, Koki, Kuroki, Kanako, Kitagawa, Daiju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777370/
https://www.ncbi.nlm.nih.gov/pubmed/31533936
http://dx.doi.org/10.1242/bio.047175