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Molecular Evolution in Small Steps under Prevailing Negative Selection: A Nearly Universal Rule of Codon Substitution

The widely accepted view that evolution proceeds in small steps is based on two premises: 1) negative selection acts strongly against large differences and 2) positive selection favors small-step changes. The two premises are not biologically connected and should be evaluated separately. We now exte...

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Detalles Bibliográficos
Autores principales: Chen, Qingjian, Lan, Ao, Shen, Xu, Wu, Chung-I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777424/
https://www.ncbi.nlm.nih.gov/pubmed/31504473
http://dx.doi.org/10.1093/gbe/evz192